Molecular Testing

Chlamydia trachomatis (CT)/Neisseria gonorrhoeae (GC)

  • The sensitivity of the CT/GC test has been shown to be superior to culture and direct specimen tests.
  • The greater sensitivity of the test permits the use of specimens other than endocervical swabs for women and urethral swabs for men. It is the only assay with urine specimen sensitivity equivalent to swab specimen.1
  • Organisms other than those we are detecting will not cause false CT/GC results1.
  • Simultaneous detection and differentiation of CT/GC in the same tube.
  • Test requires no culture growth.
  • CT/GC tests are not hindered by any excess mucus or blood present in the patient’s sample.
  • Reduces inventory and paperwork associated with multiple-collection devices.

Services

  • Offering a wider range of specimen-type alternatives:
    • Urine
    • Urethral swab
    • Endocervical swab
  • No centrifugation of specimens saves sample prep time
  • Specimens have room-temperature stability
  • High performance across multiple specimen types2
  • Non-inhibition or cross reactivity2
  • Excellent sensitivity and specificity:2

CT Assay Performance3

Specimen type Sensitivity Specificity
Endocervical Swab 84.2% 97.6%
Urine (female) 94.7% 98.9%

GC Assay Performance3

Specimen type Sensitivity Specificity
Endocervical Swab 99.2% 98.7%
Urine (female) 91.3% 99.3%

1. Gen-Probe

2. APTIMA COMBO 2® Assay for in vitro diagnostic use. San Diego, CA; Gen-Probe Incorporated; 2005.

3. Chlamydia - CDC Fact Sheet